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Full name: |
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 |
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Synonyms: |
MMTN; B17.2L; mimitin; NDUFA12L |
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Swissprot: |
Q8N183 |
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Gene Accession: |
BC033965 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene cause progressive encephalopathy resulting from mitochondrial complex I deficiency. |
